The Enzymatic Deamination of 6-Aminopyrimidine Deoxyribonucleotides

Enzymatic Synthesis of Deoxyribonucleotides

The purification and properties of an enzyme system (“Fraction B”) isolated from Escherichia coli B were recently described (1,2). It was shown that Fraction B in the presence of adenosine triphosphate, Mg”, and reduced lipoate catalyzed the formation of deoxycytidine diphosphate from cytidine diphosphate and also the formation of deoxyuridine phosphate derivatives from uridine diphosphate (UDP...

The Enzymatic Deamination of Amphetamine

A previous st,udy on the metabolism of amphetamine (1-phenyl-2-aminopropane), widely used as a stimulant of the central nervous system, showed that its major route of biotransformation in the rat and dog involved hydroxylation of the aromatic ring. In the rabbit, however, the compound was not hydroxylated, but was found to be transformed in another manner (2). The present report describes an en...

The enzymatic deamination of amphetamine (benzedrine).

Deamination of 4-aminopyrimidine nucleosides by extracts of rye grass (Lolium perenne).

A deaminase specific for 4-aminopyrimidine nucleosides has been found in rye grass. Lolium perenne. The pH optimum, temperature stability, Km values and specificity was determined.A new and more accurate method for following the course of deamination is reported. This method depends on the shift in maximum absorbance wavelength of the mixture containing the 4-aminopyrimidine nucleoside and its ...

Deamination of 4-Aminopyrimidine Nucleosides by Extracts of Rye Grass (Lolium perenne)1

Siumimiary. A deamlinlase specific for 4-aminopyrinmidine nucleosi(les has been found in rye grass. Lolimn perennle. TI'he pH optimiium., temperature stability. Km valtues and specificity ws'as determined. A new and more accurate method for following the course of deamination is reported. This metho(d depends on the shift in maximumii absorbance wavelength of the mixtuire conltaiing the 4-an-in...